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Search Results for " fatty acid synthase "

20

Compounds

Cat No. Product Name Synonyms Targets
TQ0260 Cerulenin Antibiotic , Antifungal , Fatty Acid Synthase
Cerulenin is a natural inhibitor of fatty acid synthase (FAS). It is produced by the fungus Cephalosporium caeruleus.
T11557 FASN-IN-3 Fatty Acid Synthase
FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).
T2824 Pedunculoside Others , Fatty Acid Synthase
Pedunculoside is extracted from Ilex rotunda Thunb.
T0686 Orlistat Ro-18-0647,Tetrahydrolipstatin Apoptosis , Others , Fatty Acid Synthase
Orlistat (Tetrahydrolipstatin) is an Intestinal Lipase Inhibitor. The mechanism of action of orlistat is as a Lipase Inhibitor.
T17181 TVB-3664 Fatty Acid Synthase
TVB-3664 significantly decreases tubulin palmitoylation and mRNA expression. TVB-3664 is a reversible and highly bioavailable fatty acid synthase inhibitor (IC50: 18 nM and 12 nM for human and mouse cell palmitate synthe...
T7947 FT113 Fatty Acid Synthase
FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity
T17180 TVB-3166 Apoptosis , Others , Fatty Acid Synthase
TVB-3166 induces apoptosis and inhibits in-vivo xenograft tumor growth. TVB-3166 is a reversible and selective fatty acid synthase inhibitor (IC50s: 42 nM and 81 nM for biochemical FASN and cellular palmitate synthesis,...
T7798 FGH10019 FGH-10019 NPC1L1 , Fatty Acid Synthase
FGH10019 is a novel inhibitor of sterol regulatory element-binding protein (SREBP) ( IC50 :1 μM).
T11267 FASN-IN-1 TVB-2460 Fatty Acid Synthase
FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzyme involved in fatty acid synthesis, potentially disrupting fatt...
T9266 Fatostatin Lipid , Fatty Acid Synthase
Fatostatin is a specific inhibitor of SREBP activation, it impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs.
T5S0246 Pseudoprotodioscin Others , Fatty Acid Synthase
1. Pseudoprotodioscin has moderate cytotoxicity.
TJS0387 Desoxyrhaponticin Deoxyrhapontin,Deoxyrhaponticin Apoptosis , Fatty Acid Synthase
1. Desoxyrhaponticin (Deoxyrhaponticin) is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least...
T12437 PF429242 dihydrochloride S1P Receptor
PF429242 dihydrochloride is a reversible and competitive inhibitor of S1P (IC50 of 175 nM).
T36841 IPI-9119 Fatty Acid Synthase
IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).
T10656 Trans-C75 (±)-C75 Others , Fatty Acid Synthase
trans-C75 ((±)-C75) is an enantiomer of C75. C75 is an inhibitor of fatty-acid synthase (FASN).
T3121 Betulin Trochol,betulinic alcohol,betuline,betulinol,Betulol Apoptosis , Endogenous Metabolite , Lipid , Fatty Acid Synthase
Betulin (betulinol) (lup-20(29)-ene-3β, 28-diol) is an abundant, naturally occurring triterpene. It is commonly isolated from the bark of birch trees where it forms up to 30% of the dry weight of the extractive and is fo...
T15271 Denifanstat FASN-IN-2,TVB2640,TVB-2640 Fatty Acid Synthase
Denifanstat (FASN-IN-2) is a Fatty Acid Synthase (FASN) inhibitor(IC50 of 0.052 μM and an EC50 of 0.072 μM),with potential antineoplastic activity.
T3324 Lycorine Galanthidine,Narcissine,Amarylline,Belamarine,Licorine Apoptosis , Virus Protease , Antibacterial , AChR , Fatty Acid Synthase
Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.
T3322 Trans-Chalcone Chalcone,Cinnamophenone,Chalkone Apoptosis , Others , Antifungal , Fatty Acid Synthase
trans-Chalcone (Chalkone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones.
T6832 Fatostatin hydrobromide Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin NPC1L1 , Fatty Acid Synthase
Fatostatin hydrobromide (Fatostatin A HBr) ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.

Compounds

Cerulenin
TQ0260
Synonym:
Target: Antibiotic, Antifungal, Fatty Acid Synthase
FASN-IN-3
T11557
Synonym:
Target: Fatty Acid Synthase
Pedunculoside
T2824
Synonym:
Target: Others, Fatty Acid Synthase
Orlistat
T0686
Synonym: Ro-18-0647,Tetrahydrolipstatin
Target: Apoptosis, Others, Fatty Acid Synthase
TVB-3664
T17181
Synonym:
Target: Fatty Acid Synthase
FT113
T7947
Synonym:
Target: Fatty Acid Synthase
TVB-3166
T17180
Synonym:
Target: Apoptosis, Others, Fatty Acid Synthase
FGH10019
T7798
Synonym: FGH-10019
Target: NPC1L1, Fatty Acid Synthase
FASN-IN-1
T11267
Synonym: TVB-2460
Target: Fatty Acid Synthase
Fatostatin
T9266
Synonym:
Target: Lipid, Fatty Acid Synthase
Pseudoprotodioscin
T5S0246
Synonym:
Target: Others, Fatty Acid Synthase
Desoxyrhaponticin
TJS0387
Synonym: Deoxyrhapontin,Deoxyrhaponticin
Target: Apoptosis, Fatty Acid Synthase
PF429242 dihydrochloride
T12437
Synonym:
Target: S1P Receptor
IPI-9119
T36841
Synonym:
Target: Fatty Acid Synthase
trans-C75
T10656
Synonym: (±)-C75
Target: Others, Fatty Acid Synthase
Betulin
T3121
Synonym: Trochol,betulinic alcohol,betuline,betulinol,Betulol
Target: Apoptosis, Endogenous Metabolite, Lipid, Fatty Acid Synthase
Denifanstat
T15271
Synonym: FASN-IN-2,TVB2640,TVB-2640
Target: Fatty Acid Synthase
Lycorine
T3324
Synonym: Galanthidine,Narcissine,Amarylline,Belamarine,Licorine
Target: Apoptosis, Virus Protease, Antibacterial, AChR, Fatty Acid Synthase
trans-Chalcone
T3322
Synonym: Chalcone,Cinnamophenone,Chalkone
Target: Apoptosis, Others, Antifungal, Fatty Acid Synthase
Fatostatin hydrobromide
T6832
Synonym: Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin
Target: NPC1L1, Fatty Acid Synthase
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TargetMol